Continuum theory of fibrous tissue damage mechanics using bond kinetics: application to cartilage tissue engineering
نویسندگان
چکیده
منابع مشابه
Progressive Damage Analysis of Laminated Composites using Continuum Damage Mechanics
In this paper, progressive damage and global failure of composite laminates under quasi-static, monotonic loading are investigated using 3D continuum damage mechanics. For this purpose, a finite element program has been developed using an eight-node 2D layered element including layer-wise plate theory. Damage analysis of a single orthotropic layer under various uniform in-plane and transverse l...
متن کاملImportance of Floating Chondrons in Cartilage Tissue Engineering
BACKGROUND Dedifferentiation of chondrocytes remains a major problem for cartilage tissue engineering. Chondrocytes loss differentiated phenotype in in vitro culture that is undesired for repair strategies. The chondrocyte is surrounded by a pericellular matrix (PCM), together forming the chondron. PCM has a positive effect on the maintenance of chondrocyte phenotype during culture in compar...
متن کاملTissue engineering of cartilage
The main goal of tissue engineering is to create artificial constructs that could repair or simply replace lost or damaged tissue. Common tissue engineering strategies involve the extraction of cells from a small biopsy of tissue for in vitro expansion. This culture can be carried out in a three dimensional (3D) scaffold that allows and induces the formation of new tissue after implantation. Fu...
متن کاملfabricating electrospun poly(3-hydroxybutyrate)/hydroxyapatite nanocomposite scaffold for tissue engineering application
. در رســاله ی حاضر، ابتدا داربست نانوالیاف سه بعدی متخلخل به روش الگوبرداری تصویری شبیه سازی شد. با استفاده از طراحی آزمایش به روش تاگوچی پس از ساخت داربست های پلی (3- هیدروکسی بوتیرات) (p3hb) شناسایی رفتار پارامترهای موادی مثل لزجت سیال پلیمر، فراریت و رسانایی الکتریکی محلول پلیمری و پارامترهای دستگاهی مثل دبی حجمی سیال، ولتاژ الکتریکی و فاصله نازل تا جمع کننده صورت گرفت. بعد از محاسبه ی خصوص...
Engineering cartilage tissue.
Cartilage tissue engineering is emerging as a technique for the regeneration of cartilage tissue damaged due to disease or trauma. Since cartilage lacks regenerative capabilities, it is essential to develop approaches that deliver the appropriate cells, biomaterials, and signaling factors to the defect site. The objective of this review is to discuss the approaches that have been taken in this ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Interface Focus
سال: 2016
ISSN: 2042-8898,2042-8901
DOI: 10.1098/rsfs.2015.0063